Endocrine Abstracts

The aim of the present study was to determine the change of fasting serum leptin and insulin levels and insulin resistance in patients with risk factors of diabetes mellitus of type 2 (DM 2) including impaired glucose tolerance/impaired fasting glucose (IGT/IFG).Material and methods: The study included 100 patients (32 men, 68 female) 25–65 years old at risk factors of DM 2. All patients received recommendations on a balanced diet and physical activ...

Aims: The aim of our study is to assess the efficacy of lifestyle modification and picolinate chromium intake in preventing diabetes mellitus type 2 (DM 2)Materials and methods: The study included 100 patients (69 m 258 f) 25–65 years with impaired glucose tolerance (IGT) and newly diagnosed DM 2. Patients were divided into 2 groups matched by age, weight, body mass index (BMI), waist-to-hip ratio (WHR). Research group included 54 patients who carr...

Aims: The aim of our study is to assess the efficacy of lifestyle modification in preventing diabetes mellitus type 2 (DM 2)Materials and methods: The study included 100 patients (69 m 258 f) 25–65 years with impaired glucose tolerance/impaired fasting glucose (IGT/IFG) and newly diagnosed DM 2. Patients were divided into two groups matched by sex, age, weight, BMI, waist-to-hip ratio (WHR). Research group included 54 patients who received and carri...

Aim: The aim of our study is to assess the efficacy of a lifestyle modification including altered diet composition and physical activity in preventing diabetes mellitus type 2 (DM2) in individuals with impaired glucose tolerance and impaired fasting glucose (IGT/IFG) and influence it on changes serum leptin levels.Materials and methods: The study included 327 patients with IGT/IFG (68 m, 258 f) 25-65 years. Patients were divided into two groups matched b...

Objective: To study the frequency of depression in women of reproductive age with different phenotypes of polycystic ovarian syndrome (PCOS).Materials and Methods: Sixty-eight women with diagnosed polycystic ovarian syndrome aged 18–44 and 30 practically healthy women of the comparable age. Hospital Anxiety and Depression Scales (HADS) were used to diagnose depression. According to the results of the HADS assessment, the patients were counseled by p...

Objective: To study the quality of life in women of reproductive age with different phenotypes of polycystic ovarian syndrome (PCOS).Materials and methods: 68 women with diagnosed polycystic ovarian syndrome aged 18–44 and 30 practically healthy women of the comparable age. According to the patient’s phenotype the main group was divided into 2 subgroups: patients with PCOS and obesity of varying severity (BMI> 25 kg/m2) and patie...

Objective: To estimate the frequency of night time hypoglycemic reaction cases in daily monitoring of the glucose in interstitial fluid under the conditions of DM 1.Materials and methods: The study of daily glucose dynamics was conducted with the use of the continuous glucose monitoring system made by the company Medtronik Minimed, USA. The study included 113 patients with DM 1. Patients ware divided into 2 groups: group 1 with hypoglycemic reaction case...

Objective: To study the effectiveness of therapy and the role of adherence to treatment in patients with DM and AH.Methods: A 75 patients studied with Moriski-Green test. Psycho-correctional work has been carried out with 37 people (Group 1) in order to increase motivation for treatment, and the work has not been carried out with 38 people (Group 2). The treatment effect has been evaluated after 3 months according the results of sBP and dBP dynamics and ...

Study evaluates the impact of glycemia on the parameters of night’s sleep for patients with decompensated type 1 diabetes mellitus (T1DM).Materials and methods: A total of 21 cases with T1DM (HBA1C 8.5%). The monitoring of the average daily glycemia was performed through ‘SGMSGold Medtronik’ (USA) with estimation of average level of glucose (ALG). Patients divided into groups: group A – 10 patients with A...

One of the most frequent complications of diabetes is diabetic sensorimotor peripheral polyneuropathy (DSPN). B vitamins successfully used for the treatment DSPN. However, prolonged use of vitamins B6 and B12 in effective doses limited by the comorbidities and possibility of the neurotoxic reactions development, as for vitamin B1, its low bioavailability of water-soluble forms. This determines whether the use of fat-soluble form of benfotiamine with maximum bioavailability.</p...